Advanced technological solutions need to address critical data security problems and interoperability issues that emerge from EHR systems developing in complexity. This document evaluates the combination of Blockchain technology and Artificial Intelligence tools for EHR system transformation from a business analytical standpoint. Blockchain technology maintains a secure environment through its indestructible record system and distributed computing framework that locks out breaches and unlawful data modifications thus meeting healthcare requirements of HIPAA and GDPR. AI-driven predictive analytics together with automation enables healthcare system interoperability through data organization of unstructured clinical information with optimized patient record access while providing real-time communication capabilities. This research uses quantitative methods to review securing and streamlining EHR data practices by analyzing how AI and Blockchain techniques work in current healthcare operations. The joint usage of Blockchain technology with AI creates administrative cost reductions of 30% coupled with data retrieval speed improvements totaling 40% while managing to defend healthcare facilities against over 50% of cybersecurity attacks in hazardous environments. This study outlines major challenges for extended adoption which include expensive setup costs together with problems related to standards and barriers raised by regulations. This paper connects empty research areas to deliver operational guidelines for healthcare organizations and their executive leaders and government officials seeking secure EHRs with interoperable capabilities through AI-Blockchain infrastructure deployment. The evaluation indicates Blockchain technology and AI principles hold great transformative power through strategic investments into alignment with regulations and development of infrastructure and automation powered by AI. Research must address the ongoing development of AI-Blockchain systems which will assess their effect on patients' real-time clinical care solutions and personalized medical treatments.

Blockchain, Artificial Intelligence, Electronic Health Records, Data Security, Interoperability

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