This paper investigates the evolving landscape of business model innovations within the biotechnology industry. As a pivotal sector driving technological advancements and addressing global challenges, the biotechnology industry continuously adapts its business models to capitalize on emerging opportunities and overcome inherent complexities. Drawing upon contemporary literature and empirical studies, this research explores key trends shaping business model innovations in biotechnology firms. From subscription-based models to collaborative partnerships and platform-based approaches, diverse strategies are examined to illuminate how companies are reshaping value creation, distribution channels, and revenue streams. Additionally, the paper discusses the implications of regulatory frameworks, intellectual property considerations, and market dynamics on business model innovation trajectories in the biotechnology sector.