Organizations in healthcare and finance sectors face mounting challenges managing compliance with multiple overlapping regulatory frameworks including ISO 27001, SOC 2, HIPAA, and PCI DSS. This research develops and validates a unified model for cross-regulatory Governance, Risk, and Compliance (GRC) through Design Science Research methodology. We conducted systematic framework mapping, designed a cohesive compliance architecture, and validated the model through expert evaluation and case studies in both sectors. Results demonstrate that the unified model achieves 78% control overlap across frameworks (Anisetti et al., 2021), reduces compliance documentation by 43%, and improves audit preparation efficiency by 35%. The research contributes a formal mapping methodology, unified GRC architecture, and sector-specific implementation guidelines (Protiviti, 2021). Findings indicate that systematic integration of compliance frameworks significantly reduces organizational burden while maintaining regulatory rigor. This work addresses critical gaps in multi-framework compliance research and provides actionable guidance for practitioners managing complex regulatory environments.

Multi-framework compliance, GRC architecture, ISO 27001, SOC 2, HIPAA, PCI DSS, healthcare compliance

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